Human PLEC protein (Recombinant) (N-His) (STJP005437)

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STJP005437
€410.63 - €1,796.88
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human PLEC-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: PLEC
Gene ID: 5339
Uniprot ID: PLEC_HUMAN
Immunogen Region: Asp175-Pro400
Immunogen: Homo sapiens (Human)
Post Translational Modifications Phosphorylated by CDK1.regulates dissociation from intermediate filaments during mitosis.
Function Interlinks intermediate filaments with microtubules and microfilaments and anchors intermediate filaments to desmosomes or hemidesmosomes. Could also bind muscle proteins such as actin to membrane complexes in muscle. May be involved not only in the filaments network, but also in the regulation of their dynamics. Structural component of muscle. Isoform 9 plays a major role in the maintenance of myofiber integrity.
Protein Name Plectin
Pcn
Pltn
Hemidesmosomal Protein 1
Hd1
Plectin-1
Database Links Reactome: R-HSA-2022090
Reactome: R-HSA-264870
Reactome: R-HSA-446107
Cellular Localisation Cytoplasm
Cytoskeleton
Cell Junction
Hemidesmosome
Cell Projection
Podosome
Localized To The Cortex Of Myotube Podosomes
Alternative Protein Names Plectin protein
Pcn protein
Pltn protein
Hemidesmosomal Protein 1 protein
Hd1 protein
Plectin-1 protein
PLEC protein
PLEC1 protein

Information sourced from Uniprot.org

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