Human PLAU protein (Recombinant-Active) (C-His) (STJP011762)

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STJP011762-100
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Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Active-Human PLAU-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: <0.1 EU/Mu g of the protein by the LAL method.
Gene Symbol: PLAU
Gene ID: 5328
Uniprot ID: UROK_HUMAN
Immunogen Region: Met1-Leu431
Immunogen: Homo sapiens (Human)
Post Translational Modifications Phosphorylation of Ser-158 and Ser-323 abolishes proadhesive ability but does not interfere with receptor binding. Produced as an inactive single-chain protein (pro-uPA or sc-uPA), is processed into the active disulfide-linked two-chain form of PLAU/uPA by a proteolytic event mediated, at least, by TMPRSS4.
Function Specifically cleaves the zymogen plasminogen to form the active enzyme plasmin.
Protein Name Urokinase-Type Plasminogen Activator
U-Plasminogen Activator
Upa Cleaved Into - Urokinase-Type Plasminogen Activator Long Chain A - Urokinase-Type Plasminogen Activator Short Chain A - Urokinase-Type Plasminogen Activator Chain B
Database Links Reactome: R-HSA-6798695
Reactome: R-HSA-75205
Cellular Localisation Secreted
Alternative Protein Names Urokinase-Type Plasminogen Activator protein
U-Plasminogen Activator protein
Upa Cleaved Into - Urokinase-Type Plasminogen Activator Long Chain A - Urokinase-Type Plasminogen Activator Short Chain A - Urokinase-Type Plasminogen Activator Chain B protein
PLAU protein

Information sourced from Uniprot.org

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