Human PLAA (Phospholipase A2 Activating Protein) Sandwich ELISA Kit Ready-To-Use Kit (STJE0017921)

Human PLAA (Phospholipase A2 Activating Protein) Sandwich ELISA Kit Ready-To-Use Kit (STJE0017921)

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STJE0017921
£446.50 - £611.50
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.114ng/mL
Detection Limit: 0.312-20ng/mL
Short Description : This PLAA Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma or other biological fluids..
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: PLAA
Gene ID: 9373
Uniprot ID: PLAP_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: serum, plasma or other biological fluids.
Tissue Specificity
Post Translational Modifications
Function Plays a role in protein ubiquitination, sorting and degradation through its association with VCP. Involved in ubiquitin-mediated membrane proteins trafficking to late endosomes in an ESCRT-dependent manner, and hence plays a role in synaptic vesicle recycling. May play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes. Plays a role in cerebellar Purkinje cell development. Positively regulates cytosolic and calcium-independent phospholipase A2 activities in a tumor necrosis factor alpha (TNF-alpha)- or lipopolysaccharide (LPS)-dependent manner, and hence prostaglandin E2 biosynthesis.
Protein Name Phospholipase A-2-Activating Protein
Pla2p
Plap
Database Links
Cellular Localisation Nucleus
Cytoplasm
Synapse
Recruited To Damaged Lysosomes Decorated With K48-Linked Ubiquitin Chains
Alternative ELISA Names Phospholipase A-2-Activating Protein ELISA kit
Pla2p ELISA kit
Plap ELISA kit
PLAA ELISA kit
PLAP ELISA kit
output

Information sourced from Uniprot.org

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