Human PIR protein (Recombinant) (N-His) (STJP010611)

SKU:
STJP010611
$443.48 - $1,940.63
Free Shipping
Processing The item has been added

Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human PIR-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: PIR
Gene ID: 8544
Uniprot ID: PIR_HUMAN
Immunogen Region: Met1-Asn290
Immunogen: Homo sapiens (Human)
Function Transcriptional coregulator of NF-kappa-B which facilitates binding of NF-kappa-B proteins to target kappa-B genes in a redox-state-dependent manner. May be required for efficient terminal myeloid maturation of hematopoietic cells. Has quercetin 2,3-dioxygenase activity (in vitro).
Protein Name Pirin
Probable Quercetin 2 -3-Dioxygenase Pir
Probable Quercetinase
Database Links Reactome: R-HSA-8935690
Cellular Localisation Nucleus
Cytoplasm
Predominantly Localized In Dot-Like Subnuclear Structures
Cytoplasmic Localization Of Pir Seems To Positively Correlate With Melanoma Progression
Alternative Protein Names Pirin protein
Probable Quercetin 2 -3-Dioxygenase Pir protein
Probable Quercetinase protein
PIR protein

Information sourced from Uniprot.org