Function | Transcriptional coregulator of NF-kappa-B which facilitates binding of NF-kappa-B proteins to target kappa-B genes in a redox-state-dependent manner. May be required for efficient terminal myeloid maturation of hematopoietic cells. Has quercetin 2,3-dioxygenase activity (in vitro). |
Protein Name | PirinProbable Quercetin 2 -3-Dioxygenase PirProbable Quercetinase |
Database Links | Reactome: R-HSA-8935690 |
Cellular Localisation | NucleusCytoplasmPredominantly Localized In Dot-Like Subnuclear StructuresCytoplasmic Localization Of Pir Seems To Positively Correlate With Melanoma Progression |
Alternative Protein Names | Pirin proteinProbable Quercetin 2 -3-Dioxygenase Pir proteinProbable Quercetinase proteinPIR protein |
Information sourced from Uniprot.org