| Short Description : | Recombinant-Active-Human PI3-C-10*His protein was developed from mammalian cells and has a target region of C-10*His. For use in research applications. |
| Applications: | ELISA/WB |
| Host: | Mammalian Cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | <0.1 EU/Mu g of the protein by the LAL method. |
| Immunoreactivity: | Measured by its ability to inhibit neutrophil elastase cleavage of the fluorogenic peptide substrate, MeOSuc-Ala-Ala-Pro-Val-7-amido-4-methylcoumarin (MeOSuc-AAPV-AMC). The IC50 value is <50 nM, as measured under the described conditions. |
| Gene Symbol: | PI3 |
| Gene ID: | 5266 |
| Uniprot ID: | ELAF_HUMAN |
| Immunogen: | Homo sapiens (Human) |
| Immunogen Region: | Ala23-Gln117 |
| Protein Name | ElafinElastase-Specific InhibitorEsiPeptidase Inhibitor 3Pi-3Protease Inhibitor Wap3Skin-Derived AntileukoproteinaseSkalpWap Four-Disulfide Core Domain Protein 14 |
| Database Links | Reactome: R-HSA-6803157Reactome: R-HSA-6809371 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Elafin proteinElastase-Specific Inhibitor proteinEsi proteinPeptidase Inhibitor 3 proteinPi-3 proteinProtease Inhibitor Wap3 proteinSkin-Derived Antileukoproteinase proteinSkalp proteinWap Four-Disulfide Core Domain Protein 14 proteinPI3 proteinWAP3 proteinWFDC14 protein |
Information sourced from Uniprot.org