Human PGF/PlGF/PLGF protein (Recombinant) (C-His) (STJP008629)
SPECIFICATIONS
HostMammalian Cells
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human PGF/PlGF/PLGF-C-His protein was developed from mammalian cells for the region C-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | PGF |
| Gene ID | 5228 |
| Uniprot ID | PLGF_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | leu20-Arg131 |
Additional Info
| Post Translational Modifications | N-glycosylated. |
| Function | Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth. |
| Protein Name | Placenta Growth FactorPlgf |
| Database Links | Reactome: R-HSA-194313Reactome: R-HSA-195399 |
| Cellular Localisation | SecretedThe Three Isoforms Are Secreted But Plgf-2 Appears To Remain Cell Attached Unless Released By Heparin |
| Alternative Protein Names | Placenta Growth Factor proteinPlgf proteinPGF proteinPGFL proteinPLGF protein |
Information sourced from Uniprot.org