| Host: | Goat/Goat |
| Applications: | ELISA |
| Reactivity: | Human |
| Note: | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description : | This PEDF antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Conjugation: | Unconjugated/Biotin |
| Formulation: | Capture Buffer: PBS with 0.04% Proclin 300; 50% glycerol; pH 7.5.Detection Buffer: PBS with 0.04% Proclin 300; 1% protective protein; 50% glycerol; pH 7.5. |
| Purification: | Capture Purification: Antigen Affinity.Detection Purification: Antigen Affinity. |
| Concentration: | 0.5 mg/mL |
| Storage Instruction: | Store at-20°C for long term, and avoid freeze-thaw cycles. |
| Determination Method: | Colormetric |
| Gene Symbol: | SERPINF1 |
| Gene ID: | 5176 |
| Uniprot ID: | PEDF_HUMAN |
| Immunogen: | Capture immunogen: Recombinant Human PEDF protien.Detection Immunogen: Recombinant Human PEDF protien. |
| Sample Type: | Serum, plasma and other biological fluids |
| Post Translational Modifications | The N-terminus is blocked. Extracellular phosphorylation enhances antiangiogenic activity. N- and O-glycosylated. O-glycosylated with a core 1 or possibly core 8 glycan. |
| Function | Neurotrophic protein.induces extensive neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity. |
| Protein Name | Pigment Epithelium-Derived FactorPedfCell Proliferation-Inducing Gene 35 ProteinEpc-1Serpin F1 |
| Cellular Localisation | SecretedMelanosomeEnriched In Stage I Melanosomes |
| Alternative Antibody Pair Names | Pigment Epithelium-Derived Factor antibody pairPedf antibody pairCell Proliferation-Inducing Gene 35 Protein antibody pairEpc-1 antibody pairSerpin F1 antibody pairSERPINF1 antibody pairPEDF antibody pairPIG35 antibody pair |
Information sourced from Uniprot.org