Function | Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress. Dynorphin peptides differentially regulate the kappa opioid receptor. Dynorphin A(1-13) has a typical opioid activity, it is 700 times more potent than Leu-enkephalin. Leumorphin has a typical opioid activity and may have anti-apoptotic effect. |
Protein Name | Proenkephalin-BBeta-Neoendorphin-DynorphinPreprodynorphin Cleaved Into - Alpha-Neoendorphin - Beta-Neoendorphin - Big DynorphinBig Dyn - Dynorphin A(1-17Dyn-A17Dynorphin A - Dynorphin A(1-13 - Dynorphin A(1-8 - Leu-Enkephalin - RimorphinDynorphin BDyn-BDynorphin B(1-13 - LeumorphinDynorphin B-29 |
Database Links | Reactome: R-HSA-111885Reactome: R-HSA-202040Reactome: R-HSA-375276Reactome: R-HSA-418594 |
Cellular Localisation | Secreted |
Alternative Protein Names | Proenkephalin-B proteinBeta-Neoendorphin-Dynorphin proteinPreprodynorphin Cleaved Into - Alpha-Neoendorphin - Beta-Neoendorphin - Big Dynorphin proteinBig Dyn - Dynorphin A(1-17 proteinDyn-A17 proteinDynorphin A - Dynorphin A(1-13 - Dynorphin A(1-8 - Leu-Enkephalin - Rimorphin proteinDynorphin B proteinDyn-B proteinDynorphin B(1-13 - Leumorphin proteinDynorphin B-29 proteinPDYN protein |
Information sourced from Uniprot.org