Name: Human PDIA6 protein (Recombinant) (His-Tag) (STJP016913)
SKU: STJP016913
Availability: InStock

Human PDIA6 protein (Recombinant) (His-Tag) (STJP016913)

SKU:

STJP016913

$185.61 - $1,019.13

Short Description :	Recombinant-Human PDIA6-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:	SDS-PAGE
Host:	E.coli
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration:	1 mg/mL
Formulation:	Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol, 2mM DTT, 50mM NaCl
Storage Instruction:	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Gene Symbol:	PDIA6
Gene ID:	10130
Uniprot ID:	PDIA6_HUMAN
Accession Number:	NP_005733.1
Immunogen:	Human
Immunogen Region:	20-440aa
Immunogen Sequence:	LYSSSDDVI ELTPSNFNRE VIQSDSLWLV EFYAPWCGHC QRLTPEWKKA ATALKDVVKV GAVDADKHHS LGGQYGVQGF PTIKIFGSNK NRPEDYQGGR TGEAIVDAAL SALRQLVKDR LGGRSGGYSS GKQGRSDSSS KKDVIELTDD SFDKNVLDSE DVWMVEFYAP WCGHCKNLEP EWAAAASEVK EQTKGKVKLA AVDATV

Tissue Specificity	Expressed in platelets (at protein level).
Function	May function as a chaperone that inhibits aggregation of misfolded proteins. Negatively regulates the unfolded protein response (UPR) through binding to UPR sensors such as ERN1, which in turn inactivates ERN1 signaling. May also regulate the UPR via the EIF2AK3 UPR sensor. Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin.
Protein Name	Protein Disulfide-Isomerase A6 Endoplasmic Reticulum Protein 5 Er Protein 5 Erp5 Protein Disulfide Isomerase P5 Thioredoxin Domain-Containing Protein 7
Database Links	Reactome: R-HSA-381038 Reactome: R-HSA-381426 Reactome: R-HSA-8957275
Cellular Localisation	Endoplasmic Reticulum Lumen Cell Membrane Melanosome Identified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv
Alternative Protein Names	Protein Disulfide-Isomerase A6 protein Endoplasmic Reticulum Protein 5 protein Er Protein 5 protein Erp5 protein Protein Disulfide Isomerase P5 protein Thioredoxin Domain-Containing Protein 7 protein PDIA6 protein ERP5 protein P5 protein TXNDC7 protein

Information sourced from Uniprot.org

Model	Name	Host	Application
STJP019202	Human PDIA6 protein (Recombinant) (His-Tag) (STJP019202)	E.coli	SDS-PAGE/Enzyme Activity
STJP013476	Human PDIA6 protein (Recombinant) (C-His) (STJP013476)	Mammalian Cells	ELISA/WB
STJP019690	Human IRF2 protein (Recombinant) (His-Tag) (STJP019690)	E.coli	SDS-PAGE
STJP017768	Human CSTF1 protein (Recombinant) (His-Tag) (STJP017768)	E.coli	SDS-PAGE/Denatured
STJP017869	Human RNF4 protein (Recombinant) (His-Tag) (STJP017869)	E.coli	SDS-PAGE

Human PDIA6 protein (Recombinant) (His-Tag) (STJP016913)

General Information