Human PDHa (Pyruvate Dehydrogenase Alpha) Sandwich ELISA Kit (STJE0011367)

Human PDHa (Pyruvate Dehydrogenase Alpha) Sandwich ELISA Kit (STJE0011367)

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STJE0011367
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.078ng/mL
Detection Limit: 0.156-10ng/mL
Short Description : This PDHa Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates or other biological fluids.
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: PDHA1
Gene ID: 5160
Uniprot ID: ODPA_HUMAN
Sample Type: serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity Ubiquitous.
Post Translational Modifications Phosphorylation at Ser-232, Ser-293 and Ser-300 by PDK family kinases inactivates the enzyme.for this phosphorylation at a single site is sufficient. Dephosphorylation at all three sites, i.e. at Ser-232, Ser-293 and Ser-300, is required for reactivation. Acetylation alters the phosphorylation pattern. Deacetylated by SIRT3.
Function The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
Protein Name Pyruvate Dehydrogenase E1 Component Subunit Alpha - Somatic Form - Mitochondrial
Pdhe1-A Type I
Database Links Reactome: R-HSA-204174
Reactome: R-HSA-5362517
Reactome: R-HSA-9837999
Reactome: R-HSA-9861559
Cellular Localisation Mitochondrion Matrix
Alternative ELISA Names Pyruvate Dehydrogenase E1 Component Subunit Alpha - Somatic Form - Mitochondrial ELISA kit
Pdhe1-A Type I ELISA kit
PDHA1 ELISA kit
PHE1A ELISA kit
output

Information sourced from Uniprot.org

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