Host: |
Goat/Goat |
Applications: |
ELISA |
Reactivity: |
Human |
Note: |
FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Short Description: |
This PDGF-BB antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
Conjugation: |
Unconjugated/Biotin |
Formulation: |
Capture Buffer: PBS with 0.04% Proclin 300; 50% glycerol; pH 7.5.Detection Buffer: PBS with 0.04% Proclin 300; 1% protective protein; 50% glycerol; pH 7.5. |
Purification: |
Capture Purification: Antigen Affinity.Detection Purification: Antigen Affinity. |
Concentration: |
0.5 mg/mL |
Storage Instruction: |
Store at-20°C for long term, and avoid freeze-thaw cycles. |
Determination Method: |
Colormetric |
Gene Symbol: |
PDGFB |
Gene ID: |
5155 |
Uniprot ID: |
PDGFB_HUMAN |
Immunogen: |
Capture immunogen: Recombinant Human PDGF-BB protien.Detection Immunogen: Recombinant Human PDGF-BB protien. |
Sample Type: |
Serum, plasma and other biological fluids |
Function | Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA. |
Protein Name | Platelet-Derived Growth Factor Subunit BPdgf Subunit BPdgf-2Platelet-Derived Growth Factor B ChainPlatelet-Derived Growth Factor Beta PolypeptideProto-Oncogene C-SisBecaplermin |
Database Links | Reactome: R-HSA-114608Reactome: R-HSA-1257604Reactome: R-HSA-186763Reactome: R-HSA-186797Reactome: R-HSA-2219530Reactome: R-HSA-3000171Reactome: R-HSA-5673001Reactome: R-HSA-6811558 |
Cellular Localisation | SecretedReleased By Platelets Upon Wounding |
Alternative Antibody Pair Names | Platelet-Derived Growth Factor Subunit B antibody pairPdgf Subunit B antibody pairPdgf-2 antibody pairPlatelet-Derived Growth Factor B Chain antibody pairPlatelet-Derived Growth Factor Beta Polypeptide antibody pairProto-Oncogene C-Sis antibody pairBecaplermin antibody pairPDGFB antibody pairPDGF2 antibody pairSIS antibody pair |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance