Human PDE6D protein (Recombinant) (C-Fc) (STJP010134)

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STJP010134
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Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human PDE6D-C-Fc protein was developed from mammalian cells and has a target region of C-Fc. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: PDE6D
Gene ID: 5147
Uniprot ID: PDE6D_HUMAN
Immunogen Region: Met1-Val150
Immunogen: Homo sapiens (Human)
Function Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide dissociation rate.
Protein Name Retinal Rod Rhodopsin-Sensitive Cgmp 3' -5'-Cyclic Phosphodiesterase Subunit Delta
Gmp-Pde Delta
Protein P17
Database Links Reactome: R-HSA-5624958
Reactome: R-HSA-9648002
Cellular Localisation Cytoplasm
Cytosol
Cytoplasmic Vesicle Membrane
Peripheral Membrane Protein
Cytoskeleton
Cilium Basal Body
Alternative Protein Names Retinal Rod Rhodopsin-Sensitive Cgmp 3' -5'-Cyclic Phosphodiesterase Subunit Delta protein
Gmp-Pde Delta protein
Protein P17 protein
PDE6D protein
PDED protein

Information sourced from Uniprot.org

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