Human PDE12 (Phosphodiesterase 12) Sandwich ELISA Kit Ready-To-Use Kit (STJE0017720)

Human PDE12 (Phosphodiesterase 12) Sandwich ELISA Kit Ready-To-Use Kit (STJE0017720)

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STJE0017720
$654.08 - $899.78
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.066ng/mL
Detection Limit: 0.156-10ng/mL
Short Description : This PDE12 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates or other biological fluids..
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: PDE12
Gene ID: 201626
Uniprot ID: PDE12_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity Ubiquitous.
Post Translational Modifications
Function Enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the 5'-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modulates the 2-5A system. Degrades triphosphorylated 2-5A to produce AMP and ATP. Also cleaves 3',5'-phosphodiester bond of oligoadenylates. Plays a role as a negative regulator of the 2-5A system that is one of the major pathways for antiviral and antitumor functions induced by interferons (IFNs). Suppression of this enzyme increases cellular 2-5A levels and decreases viral replication in cultured small-airway epithelial cells and Hela cells.
Protein Name 2' -5'-Phosphodiesterase 12
2'-Pde
2-Pde
Mitochondrial Deadenylase
Database Links Reactome: R-HSA-8983711
Cellular Localisation Mitochondrion Matrix
Alternative ELISA Names 2' -5'-Phosphodiesterase 12 ELISA kit
2'-Pde ELISA kit
2-Pde ELISA kit
Mitochondrial Deadenylase ELISA kit
PDE12 ELISA kit
output

Information sourced from Uniprot.org

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