Human PDCL3 protein (Recombinant) (His-Tag) (STJP017506)

Name: Human PDCL3 protein (Recombinant) (His-Tag) (STJP017506)
SKU: STJP017506
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostE.coli

ImmunogenHuman

STJP017506

Current Stock:

🚚 Free UK Delivery on orders over £150

Quantity:

Processing The item has been added

Enquire For Bulk Order

✓ 1-Year Performance Guarantee | SDS & Datasheet Included | Expert Tech Support | Covered by St John's Laboratory Guarantee

Short Description	Recombinant-Human PDCL3-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications	SDS-PAGE
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration	1 mg/mL
Formulation	Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol, 0.1M NaCl
Storage Instruction	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Gene Symbol	PDCL3
Gene ID	79031
Uniprot ID	PDCL3_HUMAN
Accession Number	NP_076970
Immunogen	Human
Immunogen Region	1-239aa
Immunogen Sequence	MQDPNAD TEWNDILRKK GILPPKESLK ELEEEAEEEQ RILQQSVVKT YEDMTLEELE DHEDEFNEED ERAIEMYRRR RLAEWKATKL KNKFGEVLEI SGKDYVQEVT KAGEGLWVIL HLYKQGIPLC ALINQHLSGL ARKFPDVKFI KAISTTCIPN YPDRNLPTIF VYLEGDIKAQ FIGPLVFGGM NLTRDELEWK LSESGA

Tissue Specificity	Expressed in endothelial cells (at protein level). Expressed in all tissues examined including spleen, thymus, prostate, testis, ovary, small intestine and colon.
Post Translational Modifications	N-terminal methionine acetylation destabilizes the protein.
Function	Acts as a chaperone for the angiogenic VEGF receptor KDR/VEGFR2, increasing its abundance by inhibiting its ubiquitination and degradation. Inhibits the folding activity of the chaperonin-containing T-complex (CCT) which leads to inhibition of cytoskeletal actin folding. Acts as a chaperone during heat shock alongside HSP90 and HSP40/70 chaperone complexes. Modulates the activation of caspases during apoptosis.
Protein Name	Phosducin-Like Protein 3 Htphlp Phpl3 Viral Iap-Associated Factor 1 Viaf-1
Database Links
Cellular Localisation	Cytoplasm Perinuclear Region Endoplasmic Reticulum
Alternative Protein Names	Phosducin-Like Protein 3 protein Htphlp protein Phpl3 protein Viral Iap-Associated Factor 1 protein Viaf-1 protein PDCL3 protein PhLP2A protein VIAF1 protein

Information sourced from Uniprot.org