Human PARVA protein (Recombinant) (C-His) (STJP014750)

Name: Human PARVA protein (Recombinant) (C-His) (STJP014750)
SKU: STJP014750-100
Price: 575.5 GBP
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostE.coli

ConjugationUnconjugated

ImmunogenHomo sapiens (Human)

STJP014750-100

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Short Description	Recombinant-Human PARVA-C-His protein was developed from e.coli and has a target region of C-His. For use in research applications.
Applications	ELISA/WB
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Conjugation	Unconjugated
Formulation	Supplied as a 0.22 Mu m filtered solution in 50mM Tris-HCl, 150mM NaCl, 40% Glycerol, pH 7.4.
Storage Instruction	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin	< 1 EU/µg as determined by LAL test.

Function	Plays a role in sarcomere organization and in smooth muscle cell contraction. Required for normal development of the embryonic cardiovascular system, and for normal septation of the heart outflow tract. Plays a role in sprouting angiogenesis and is required for normal adhesion of vascular smooth muscle cells to endothelial cells during blood vessel development. Plays a role in the reorganization of the actin cytoskeleton, formation of lamellipodia and ciliogenesis. Plays a role in the establishment of cell polarity, cell adhesion, cell spreading, and directed cell migration. Within the IPP (ILK-PINCH-PARVIN) complex, binds to F-actin, promoting F-actin bundling, a process required to generate force for actin cytoskeleton reorganization and subsequent dynamic cell adhesion events such as cell spreading and migration.
Protein Name	Alpha-Parvin Actopaxin Ch-Ilkbp Calponin-Like Integrin-Linked Kinase-Binding Protein Matrix-Remodeling-Associated Protein 2
Database Links	Reactome: R-HSA-446343 Reactome: R-HSA-446353 Reactome: R-HSA-446388
Cellular Localisation	Cell Junction Focal Adhesion Cell Membrane Peripheral Membrane Protein Cytoplasmic Side Cytoplasm Cytoskeleton Myofibril Sarcomere Z Line
Alternative Protein Names	Alpha-Parvin protein Actopaxin protein Ch-Ilkbp protein Calponin-Like Integrin-Linked Kinase-Binding Protein protein Matrix-Remodeling-Associated Protein 2 protein PARVA protein MXRA2 protein

Information sourced from Uniprot.org