| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 0.064ng/mL |
| Detection Limit: | 0.156-10ng/mL |
| Short Description: | This PANK4 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids.. |
| Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 3 hrs |
| Gene Symbol: | PANK4 |
| Gene ID: | 55229 |
| Uniprot ID: | PANK4_HUMAN |
| Immunogen Region: | Ready-To-Use |
| Sample Type: | tissue homogenates or other biological fluids. |
| Tissue Specificity | Widely expressed with high expression in the muscle. Expressed in the retina and lens epithelium, mainly in ganglion cell layer, outer plexiform layer and retinal pigment layer (at protein level). |
| Post Translational Modifications | |
| Function | Phosphatase which shows a preference for 4'-phosphopantetheine and its oxidatively damaged forms (sulfonate or S-sulfonate), providing strong indirect evidence that the phosphatase activity pre-empts damage in the coenzyme A (CoA) pathway. Hydrolyzing excess 4'-phosphopantetheine could constitute a directed overflow mechanism to prevent its oxidation to the S-sulfonate, sulfonate, or other forms. Hydrolyzing 4'-phosphopantetheine sulfonate or S-sulfonate would forestall their conversion to inactive forms of CoA and acyl carrier protein. May play a role in the physiological regulation of CoA intracellular levels (Probable). |
| Protein Name | 4'-Phosphopantetheine Phosphatase Inactive Pantothenic Acid Kinase 4 Hpank4 |
| Database Links | Reactome: R-HSA-199220 |
| Cellular Localisation | Cytoplasm |
| Alternative ELISA Names | 4'-Phosphopantetheine Phosphatase ELISA kit Inactive Pantothenic Acid Kinase 4 ELISA kit Hpank4 ELISA kit PANK4 ELISA kit |
| output |
Information sourced from Uniprot.org
