Human PACS2 protein (Recombinant) (N-His) (STJP010974)

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STJP010974
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human PACS2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: PACS2
Gene ID: 23241
Uniprot ID: PACS2_HUMAN
Immunogen Region: Met22-His181
Immunogen: Homo sapiens (Human)
Function Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptotic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death. May also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments.
Protein Name Phosphofurin Acidic Cluster Sorting Protein 2
Pacs-2
Pacs1-Like Protein
Cellular Localisation Endoplasmic Reticulum
Mitochondrion
Alternative Protein Names Phosphofurin Acidic Cluster Sorting Protein 2 protein
Pacs-2 protein
Pacs1-Like Protein protein
PACS2 protein
KIAA0602 protein
PACS1L protein

Information sourced from Uniprot.org

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