Human PA28 alpha/PSME1 protein (Recombinant) (His-Tag) (STJP016889)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human PA28 alpha/PSME1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PSME1 |
| Gene ID | 5720 |
| Uniprot ID | PSME1_HUMAN |
| Accession Number | NP_006254 |
| Immunogen | Human |
| Immunogen Region | 1-249aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MAMLRVQPEA QAKVDVFRED LCTKTENLLG SYFPKKISEL DAFLKEPALN EANLSNLKAP LDIPVPDPVK EKEKEERKKQ QEKEDKDEKK KGEDEDKGPP CGPVNCNEKI VVLLQRLKPE IKDVIEQLNL VTTWLQLQIP RIEDGNNFGV AVQEKVFELM TSLHTKLEGF HTQISKYFSE RGDAVTKAAK QPHVGDYRQL VHELDEAE |
Additional Info
| Function | Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome. |
| Protein Name | Proteasome Activator Complex Subunit 111s Regulator Complex Subunit AlphaReg-AlphaActivator Of Multicatalytic Protease Subunit 1Interferon Gamma Up-Regulated I-5111 ProteinIgup I-5111Proteasome Activator 28 Subunit AlphaPa28aPa28alpha |
| Database Links | Reactome: R-HSA-9907900 |
| Cellular Localisation | |
| Alternative Protein Names | Proteasome Activator Complex Subunit 1 protein11s Regulator Complex Subunit Alpha proteinReg-Alpha proteinActivator Of Multicatalytic Protease Subunit 1 proteinInterferon Gamma Up-Regulated I-5111 Protein proteinIgup I-5111 proteinProteasome Activator 28 Subunit Alpha proteinPa28a proteinPa28alpha proteinPSME1 proteinIFI5111 protein |
Information sourced from Uniprot.org