Human OSX (Osterix) Sandwich ELISA Kit (STJE0011218)
SPECIFICATIONS
General Information
| Short Description | This OSX Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.125ng/mL |
| Detection Limit | 0.312-20ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | SP7 |
| Gene ID | 121340 |
| Uniprot ID | SP7_HUMAN |
| Sample Type | tissue homogenates, cell lysates or other biological fluids. |
Additional Info
| Tissue Specificity | Restricted to bone-derived cell. |
| Post Translational Modifications | Ubiquitination at leads to proteasomal degradation. SP7 is a short-live protein with an endogenous half-life of approximately 12 hours. Propionylated. Depropionylation at Lys-371 by SIRT7 activates transcription factor activity and positively regulates bone formation by osteoblasts. |
| Function | Transcriptional activator essential for osteoblast differentiation. Binds to SP1 and EKLF consensus sequences and to other G/C-rich sequences. |
| Protein Name | Transcription Factor Sp7Zinc Finger Protein Osterix |
| Database Links | Reactome: R-HSA-8940973 |
| Cellular Localisation | Nucleus |
| Alternative ELISA Names | Transcription Factor Sp7 ELISA kitZinc Finger Protein Osterix ELISA kitSP7 ELISA kitOSX ELISA kit |
| output |
Information sourced from Uniprot.org