Human Osteonectin/SPARC protein (Recombinant) (C-His) (STJP000988)

SKU:

STJP000988

£59.50 - £156.50

Host:	HEK293 cells
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Recombinant-Human Osteonectin/SPARC-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications.

Formulation:

Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.

Gene Symbol:	SPARC
Gene ID:	6678
Uniprot ID:	SPRC_HUMAN
Immunogen:	Recombinant Human Osteonectin/SPARC Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala18-Ile303) of human Osteonectin/SPARC (Accession #NP_003109.1) fused with a 6×His tag at the C-terminus.

Function	Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites.an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.
Protein Name	Sparc Basement-Membrane Protein 40 Bm-40 Osteonectin On Secreted Protein Acidic And Rich In Cysteine
Database Links	Reactome: R-HSA-114608 Reactome: R-HSA-1251985 Reactome: R-HSA-3000178 Reactome: R-HSA-3000497
Cellular Localisation	Secreted Extracellular Space Extracellular Matrix Basement Membrane In Or Around The Basement Membrane
Alternative Protein Names	Sparc protein Basement-Membrane Protein 40 protein Bm-40 protein Osteonectin protein On protein Secreted Protein Acidic And Rich In Cysteine protein SPARC protein ON protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance