| Host: |
HEK293 cells |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: |
Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: |
< 0.1 EU/Mu g of the protein by LAL method. |
| Gene Symbol: |
GPNMB |
| Gene ID: |
10457 |
| Uniprot ID: |
GPNMB_HUMAN |
| Immunogen: |
Recombinant Human Osteoactivin/GPNMB Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Met1-Pro474) of human GPNMB (Accession #NP_002501.1) fused with an Fc, 6×His tag at the C-terminus. |
| Immunogen Sequence: |
MECLYYFLGFLLLAARLPLD AAKRFHDVLGNERPSAYMRE HNQLNGWSSDENDWNEKLYP VWKRGDMRWKNSWKGGRVQA VLTSDSPALVGSNITFAVNL IFPRCQKEDANGNIVYEKNC RNEAGLSADPYVYNWTAWSE DSDGENGTGQSHHNVFPDGK PFPHHPGWRRWNFIYVFHTL GQYFQKLGRCSVRVSVNTAN VTLGPQLMEVTVYRRHGRAY VPIAQVKDVYVVTDQIPVF |
| Function | Could be a melanogenic enzyme. |
| Protein Name | Transmembrane Glycoprotein NmbHematopoietic Growth Factor Inducible Neurokinin-1 Type |
| Database Links | Reactome: R-HSA-8857538 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinMelanosome MembraneEarly Endosome MembraneIdentified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv |
| Alternative Protein Names | Transmembrane Glycoprotein Nmb proteinHematopoietic Growth Factor Inducible Neurokinin-1 Type proteinGPNMB proteinHGFIN proteinNMB proteinUNQ1725 proteinPRO9925 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
