Host: | Mammalian Cells |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Recombinant-Human OSMR/IL-31RB-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
Formulation: | Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Gene Symbol: | OSMR |
Gene ID: | 9180 |
Uniprot ID: | OSMR_HUMAN |
Immunogen Region: | Met1-Met740 |
Immunogen: | Homo sapiens (Human) |
Function | Associates with IL31RA to form the IL31 receptor. Binds IL31 to activate STAT3 and possibly STAT1 and STAT5. Capable of transducing OSM-specific signaling events. |
Protein Name | Oncostatin-M-Specific Receptor Subunit BetaInterleukin-31 Receptor Subunit BetaIl-31 Receptor Subunit BetaIl-31r Subunit BetaIl-31r-BetaIl-31rb |
Database Links | Reactome: R-HSA-6788467 |
Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
Alternative Protein Names | Oncostatin-M-Specific Receptor Subunit Beta proteinInterleukin-31 Receptor Subunit Beta proteinIl-31 Receptor Subunit Beta proteinIl-31r Subunit Beta proteinIl-31r-Beta proteinIl-31rb proteinOSMR proteinOSMRB protein |
Information sourced from Uniprot.org