human Olfactomedin-4/OLFM4 protein (Recombinant) (C-6His) (STJP001934)

human Olfactomedin-4/OLFM4 protein (Recombinant) (C-6His) (STJP001934)

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STJP001934
€154.38 - €533.13
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Host: HEK293 cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Formulation: Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method: <1 EU/Mu g
Gene Symbol: OLFM4
Gene ID: 10562
Uniprot ID: OLFM4_HUMAN
Immunogen Region: Asp21-Gln510
Immunogen: Recombinant human Olfactomedin-4/OLFM4 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Asp21-Gln510) of human Olfactomedin-4/OLFM4 (Accession #NP_006409.3) fused with a 6×His tag at the C-terminus
Immunogen Sequence: DLGDVGPPIPSPGFSSFPGV DSSSSFSSSSRSGSSSSRSL GSGGSVSQLFSNFTGSVDDR GTCQCSVSLPDTTFPVDRVE RLEFTAHVLSQKFEKELSKV REYVQLISVYEKKLLNLTVR IDIMEKDTISYTELDFELIK VEVKEMEKLVIQLKESFGGS SEIVDQLEVEIRNMTLLVEK LETLDKNNVLAIRREIVALK TKLKECEASKDQNTPVVHPP PTPGSCGHGGVVNISKPSV
Post Translational Modifications N-glycosylated.
Function May promote proliferation of pancreatic cancer cells by favoring the transition from the S to G2/M phase. In myeloid leukemic cell lines, inhibits cell growth and induces cell differentiation and apoptosis. May play a role in the inhibition of EIF4EBP1 phosphorylation/deactivation. Facilitates cell adhesion, most probably through interaction with cell surface lectins and cadherin.
Protein Name Olfactomedin-4
Olm4
Antiapoptotic Protein Gw112
G-Csf-Stimulated Clone 1 Protein
Hgc-1
Holfd
Database Links Reactome: R-HSA-6798695
Cellular Localisation Secreted
Extracellular Space
Mitochondrion
Subcellular Location Is Not Clearly Defined: Has Been Shown To Be Secreted
But Also In The Mitochondrion
Cytoplasm And Plasma Membrane And In The Nucleus
Alternative Protein Names Olfactomedin-4 protein
Olm4 protein
Antiapoptotic Protein Gw112 protein
G-Csf-Stimulated Clone 1 Protein protein
Hgc-1 protein
Holfd protein
OLFM4 protein
GW112 protein
UNQ362 protein
PRO698 protein

Information sourced from Uniprot.org

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