Human NUDT7 protein (Recombinant) (N-His) (STJP010845)

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STJP010845
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human NUDT7-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: NUDT7
Gene ID: 283927
Uniprot ID: NUDT7_HUMAN
Immunogen Region: Met1-Leu238
Immunogen: Homo sapiens (Human)
Function Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate. Cleaves CoA, CoA esters and oxidized CoA with similar efficiencies. Preferentially hydrolyzes medium-chain acyl-CoAs and bile acid-CoAs. Has no activity toward NDP-sugars, CDP-alcohols, (deoxy)nucleoside 5'-triphosphates, nucleoside 5'-di or monophosphates, diadenosine polyphosphates, NAD, NADH, NADP, NADPH or thymidine-5'-monophospho-p-nitrophenyl ester. May be required to eliminate oxidized CoA from peroxisomes, or regulate CoA and acyl-CoA levels in this organelle in response to metabolic demand. Does not play a role in U8 snoRNA decapping activity. Binds U8 snoRNA. Exhibits decapping activity towards dpCoA-capped RNAs in vitro.
Protein Name Peroxisomal Coenzyme A Diphosphatase Nudt7
Nucleoside Diphosphate-Linked Moiety X Motif 7
Nudix Motif 7
Database Links Reactome: R-HSA-390918
Reactome: R-HSA-9033241
Cellular Localisation Peroxisome
Alternative Protein Names Peroxisomal Coenzyme A Diphosphatase Nudt7 protein
Nucleoside Diphosphate-Linked Moiety X Motif 7 protein
Nudix Motif 7 protein
NUDT7 protein

Information sourced from Uniprot.org

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