| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human NUCB1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | NUCB1 |
| Gene ID: | 4924 |
| Uniprot ID: | NUCB1_HUMAN |
| Immunogen Region: | Glu37-Leu461 |
| Immunogen: | Homo sapiens (Human) |
| Post Translational Modifications | O-glycosylated. |
| Function | Major calcium-binding protein of the Golgi which may have a role in calcium homeostasis. Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates alpha subunits of guanine nucleotide-binding proteins (G proteins). |
| Protein Name | Nucleobindin-1Calnuc |
| Database Links | Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
| Cellular Localisation | Golgi ApparatusCis-Golgi Network MembranePeripheral Membrane ProteinLumenal SideCytoplasmSecretedA Small Fraction Of The Protein May Be Cytoplasmic |
| Alternative Protein Names | Nucleobindin-1 proteinCalnuc proteinNUCB1 proteinNUC protein |
Information sourced from Uniprot.org