Human NSD3/WHSC1L1 protein (Recombinant) (N-His) (STJP008948)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human NSD3/WHSC1L1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | NSD3 |
| Gene ID | 54904 |
| Uniprot ID | NSD3_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Lys267-Thr391 |
Additional Info
| Function | Histone methyltransferase. Preferentially dimethylates 'Lys-4' and 'Lys-27' of histone H3 forming H3K4me2 and H3K27me2. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, while 'Lys-27' is a mark for transcriptional repression. |
| Protein Name | Histone-Lysine N-Methyltransferase Nsd3Nuclear Set Domain-Containing Protein 3Protein WhistleWhsc1-Like 1 Isoform 9 With Methyltransferase Activity To LysineWolf-Hirschhorn Syndrome Candidate 1-Like Protein 1Whsc1-Like Protein 1 |
| Database Links | Reactome: R-HSA-3214841 |
| Cellular Localisation | NucleusChromosome |
| Alternative Protein Names | Histone-Lysine N-Methyltransferase Nsd3 proteinNuclear Set Domain-Containing Protein 3 proteinProtein Whistle proteinWhsc1-Like 1 Isoform 9 With Methyltransferase Activity To Lysine proteinWolf-Hirschhorn Syndrome Candidate 1-Like Protein 1 proteinWhsc1-Like Protein 1 proteinNSD3 proteinWHSC1L1 proteinDC28 protein |
Information sourced from Uniprot.org