Human NSD3/WHSC1L1 protein (Recombinant) (N-His) (STJP008948)

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STJP008948
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Covered by St John's Laboratory Guarantee

Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human NSD3/WHSC1L1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: NSD3
Gene ID: 54904
Uniprot ID: NSD3_HUMAN
Immunogen Region: Lys267-Thr391
Immunogen: Homo sapiens (Human)
Function Histone methyltransferase. Preferentially dimethylates 'Lys-4' and 'Lys-27' of histone H3 forming H3K4me2 and H3K27me2. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation, while 'Lys-27' is a mark for transcriptional repression.
Protein Name Histone-Lysine N-Methyltransferase Nsd3
Nuclear Set Domain-Containing Protein 3
Protein Whistle
Whsc1-Like 1 Isoform 9 With Methyltransferase Activity To Lysine
Wolf-Hirschhorn Syndrome Candidate 1-Like Protein 1
Whsc1-Like Protein 1
Database Links Reactome: R-HSA-3214841
Cellular Localisation Nucleus
Chromosome
Alternative Protein Names Histone-Lysine N-Methyltransferase Nsd3 protein
Nuclear Set Domain-Containing Protein 3 protein
Protein Whistle protein
Whsc1-Like 1 Isoform 9 With Methyltransferase Activity To Lysine protein
Wolf-Hirschhorn Syndrome Candidate 1-Like Protein 1 protein
Whsc1-Like Protein 1 protein
NSD3 protein
WHSC1L1 protein
DC28 protein

Information sourced from Uniprot.org

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