| Host: | Mammalian Cells |
| Applications: | ELISA/WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human NPTN-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilized from a 0.22 Mu m filtered solution in 20mM PB, 150mM NaCl, pH 7.2. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | < 1 EU/µg as determined by LAL test. |
| Gene Symbol: | NPTN |
| Gene ID: | 27020 |
| Uniprot ID: | NPTN_HUMAN |
| Immunogen Region: | Gln29-His220 |
| Immunogen: | Homo sapiens (Human) |
| Function | Probable homophilic and heterophilic cell adhesion molecule involved in long term potentiation at hippocampal excitatory synapses through activation of p38MAPK. May also regulate neurite outgrowth by activating the FGFR1 signaling pathway. May play a role in synaptic plasticity. Also acts as a chaperone for ATP2B1.stabilizes ATP2B1 and increases its ATPase activity. Promotes localization of XKR8 at the cell membrane. |
| Protein Name | NeuroplastinStromal Cell-Derived Receptor 1Sdr-1 |
| Database Links | Reactome: R-HSA-977443 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: Postsynaptic Density |
| Alternative Protein Names | Neuroplastin proteinStromal Cell-Derived Receptor 1 proteinSdr-1 proteinNPTN proteinSDFR1 proteinSDR1 protein |
Information sourced from Uniprot.org