Human NOSIP protein (Recombinant) (N-His) (STJP006254)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human NOSIP-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | NOSIP |
| Gene ID | 51070 |
| Uniprot ID | NOSIP_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Gly62-Ser295 |
Additional Info
| Function | E3 ubiquitin-protein ligase that is essential for proper development of the forebrain, the eye, and the face. Catalyzes monoubiquitination of serine/threonine-protein phosphatase 2A (PP2A) catalytic subunit PPP2CA/PPP2CB. Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity. |
| Protein Name | Nitric Oxide Synthase-Interacting ProteinE3 Ubiquitin-Protein Ligase NosipRing-Type E3 Ubiquitin Transferase NosipEnos-Interacting Protein |
| Database Links | Reactome: R-HSA-203754 |
| Cellular Localisation | CytoplasmNucleusTranslocates From Nucleus To Cytoplasm In The G2 Phase Of The Cell Cycle |
| Alternative Protein Names | Nitric Oxide Synthase-Interacting Protein proteinE3 Ubiquitin-Protein Ligase Nosip proteinRing-Type E3 Ubiquitin Transferase Nosip proteinEnos-Interacting Protein proteinNOSIP proteinCGI-25 protein |
Information sourced from Uniprot.org