Human NOSIP (Nitric Oxide Synthase Interacting Protein) Ready-To-Use Sandwich ELISA Kit (STJE0017403)

Human NOSIP (Nitric Oxide Synthase Interacting Protein) Ready-To-Use Sandwich ELISA Kit (STJE0017403)

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STJE0017403
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.053ng/mL
Detection Limit: 0.156-10ng/mL
Short Description : This NOSIP Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids.
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: NOSIP
Gene ID: 51070
Uniprot ID: NOSIP_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Expressed in heart, brain and lung. Present in endothelial cells (at protein level).
Post Translational Modifications
Function E3 ubiquitin-protein ligase that is essential for proper development of the forebrain, the eye, and the face. Catalyzes monoubiquitination of serine/threonine-protein phosphatase 2A (PP2A) catalytic subunit PPP2CA/PPP2CB. Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity.
Protein Name Nitric Oxide Synthase-Interacting Protein
E3 Ubiquitin-Protein Ligase Nosip
Ring-Type E3 Ubiquitin Transferase Nosip
Enos-Interacting Protein
Database Links Reactome: R-HSA-203754
Cellular Localisation Cytoplasm
Nucleus
Translocates From Nucleus To Cytoplasm In The G2 Phase Of The Cell Cycle
Alternative ELISA Names Nitric Oxide Synthase-Interacting Protein ELISA kit
E3 Ubiquitin-Protein Ligase Nosip ELISA kit
Ring-Type E3 Ubiquitin Transferase Nosip ELISA kit
Enos-Interacting Protein ELISA kit
NOSIP ELISA kit
CGI-25 ELISA kit
output

Information sourced from Uniprot.org

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