Human NME5 protein (Recombinant) (N-His) (STJP004983)

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STJP004983
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human NME5-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: NME5
Gene ID: 8382
Uniprot ID: NDK5_HUMAN
Immunogen Region: Ile3-Lys194
Immunogen: Homo sapiens (Human)
Function Functions as part of axonemal radial spoke complexes that play an important part in the motility of sperm and cilia. Does not seem to have nucleoside diphosphate kinase (NDPK) activity. Confers protection from cell death by BAX and alters the cellular levels of several antioxidant enzymes including GPX5. May play a role in spermiogenesis by increasing the ability of late-stage spermatids to eliminate reactive oxygen species. Exhibits a 3'-5' exonuclease activity with a preference for single-stranded DNA, suggesting roles in DNA proofreading and repair.
Protein Name Nucleoside Diphosphate Kinase Homolog 5
Ndk-H 5
Ndp Kinase Homolog 5
3'-5' Exonuclease Nme5
Inhibitor Of P53-Induced Apoptosis-Beta
Ipia-Beta
Testis-Specific Nm23 Homolog
Nm23-H5
Cellular Localisation Cell Projection
Cilium
Cytoplasm
Cytoskeleton
Flagellum Axoneme
Alternative Protein Names Nucleoside Diphosphate Kinase Homolog 5 protein
Ndk-H 5 protein
Ndp Kinase Homolog 5 protein
3'-5' Exonuclease Nme5 protein
Inhibitor Of P53-Induced Apoptosis-Beta protein
Ipia-Beta protein
Testis-Specific Nm23 Homolog protein
Nm23-H5 protein
NME5 protein

Information sourced from Uniprot.org

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