| Host: | E.coli |
| Applications: | ELISA/Immunogen/SDS-PAGE/WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human NKX6-1-N-His-SUMO protein was developed from e.coli and has a target region of N-His-SUMO. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | NKX6-1 |
| Gene ID: | 4825 |
| Uniprot ID: | NKX61_HUMAN |
| Immunogen Region: | Thr242-Glu320 |
| Immunogen: | Homo sapiens (Human) |
| Function | Transcription factor which binds to specific A/T-rich DNA sequences in the promoter regions of a number of genes. Involved in the development of insulin-producing beta cells in the islets of Langerhans at the secondary transition. Together with NKX2-2 and IRX3 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class II proteins of neuronal progenitor factors, which are induced by SHH signals. |
| Protein Name | Homeobox Protein Nkx-6.1Homeobox Protein Nk-6 Homolog A |
| Database Links | Reactome: R-HSA-210745Reactome: R-HSA-210747Reactome: R-HSA-9925561 |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | Homeobox Protein Nkx-6.1 proteinHomeobox Protein Nk-6 Homolog A proteinNKX6-1 proteinNKX6A protein |
Information sourced from Uniprot.org