Human NKRF (NFKB Repressing Factor) Sandwich ELISA Kit (STJE0010981)
SPECIFICATIONS
General Information
| Short Description | This NKRF Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.126ng/mL |
| Detection Limit | 0.312-20ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | NKRF |
| Gene ID | 55922 |
| Uniprot ID | NKRF_HUMAN |
| Sample Type | tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | Widely and constitutively expressed. Expressed at lower level in colon, peripheral blood lymphocytes, lung and kidney. |
| Post Translational Modifications | |
| Function | Enhances the ATPase activity of DHX15 by acting like a brace that tethers mobile sections of DHX15 together, stabilizing a functional conformation with high RNA affinity of DHX15. Involved in the constitutive silencing of the interferon beta promoter, independently of the virus-induced signals, and in the inhibition of the basal and cytokine-induced iNOS promoter activity. Also involved in the regulation of IL-8 transcription. May also act as a DNA-binding transcription regulator: interacts with a specific negative regulatory element (NRE) 5'-AATTCCTCTGA-3' to mediate transcriptional repression of certain NK-kappa-B responsive genes. |
| Protein Name | Nf-Kappa-B-Repressing FactorNfkb-Repressing FactorNrfProtein Itba4 |
| Database Links | |
| Cellular Localisation | NucleusNucleolus |
| Alternative ELISA Names | Nf-Kappa-B-Repressing Factor ELISA kitNfkb-Repressing Factor ELISA kitNrf ELISA kitProtein Itba4 ELISA kitNKRF ELISA kitITBA4 ELISA kitNRF ELISA kit |
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Information sourced from Uniprot.org