Human NKp30 protein (Recombinant) (Fc-Tag) (STJP001859)
SPECIFICATIONS
ConjugationUnconjugated
General Information
| Short Description | Recombinant-Human NKp30-Fc-Tag protein was developed from and has a target region of Fc-Tag. For use in research applications. |
| Note | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
Target Information
| Gene Symbol | NCR3 |
| Gene ID | 259197 |
| Uniprot ID | NCTR3_HUMAN |
Additional Info
| Function | Cell membrane receptor of natural killer/NK cells that is activated by binding of extracellular ligands including BAG6 and NCR3LG1. Stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of NCR3 by BAG6 also promotes myeloid dendritic cells (DC) maturation, both through killing DCs that did not acquire a mature phenotype, and inducing the release by NK cells of TNFA and IFNG which promote DC maturation. |
| Protein Name | Natural Cytotoxicity Triggering Receptor 3Activating Natural Killer Receptor P30Natural Killer Cell P30-Related ProteinNk-P30Nkp30Cd Antigen Cd337 |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Natural Cytotoxicity Triggering Receptor 3 proteinActivating Natural Killer Receptor P30 proteinNatural Killer Cell P30-Related Protein proteinNk-P30 proteinNkp30 proteinCd Antigen Cd337 proteinNCR3 protein1C7 proteinLY117 protein |
Information sourced from Uniprot.org