Human NKp30/NCR3 protein (Recombinant) (His-Tag) (STJP018682)

SKU:
STJP018682
£134.50 - £738.50
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Short Description :Recombinant-Human NKp30/NCR3-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:0.5 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% Glycerol, 1mM DTT
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:NCR3
Gene ID:259197
Uniprot ID:NCTR3_HUMAN
Accession Number:NP_001138939
Immunogen:Human
Immunogen Region:19-138aa
Immunogen Sequence:MGSSHHHHHH SSGLVPRGSH MLWVSQPPEI RTLEGSSAFL PCSFNASQGR LAIGSVTWFR DEVVPGKEVR NGTPEFRGRL APLASSRFLH DHQAELHIRD VRGHDASIYV CRVEVLGLGV GTGNGTRLVV EKEHPQLGAG T
Tissue Specificity Selectively expressed by all resting and activated NK cells and weakly expressed in spleen.
Function Cell membrane receptor of natural killer/NK cells that is activated by binding of extracellular ligands including BAG6 and NCR3LG1. Stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of NCR3 by BAG6 also promotes myeloid dendritic cells (DC) maturation, both through killing DCs that did not acquire a mature phenotype, and inducing the release by NK cells of TNFA and IFNG which promote DC maturation.
Protein Name Natural Cytotoxicity Triggering Receptor 3
Activating Natural Killer Receptor P30
Natural Killer Cell P30-Related Protein
Nk-P30
Nkp30
Cd Antigen Cd337
Database Links Reactome: R-HSA-198933
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Natural Cytotoxicity Triggering Receptor 3 protein
Activating Natural Killer Receptor P30 protein
Natural Killer Cell P30-Related Protein protein
Nk-P30 protein
Nkp30 protein
Cd Antigen Cd337 protein
NCR3 protein
1C7 protein
LY117 protein

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJP002593 Human NCR3/NKp30/CD337 protein (Recombinant) (C-hFc & His) (STJP002593) HEK293 cells
STJP001661 Human NKp30/NCR3/CD337 protein (Recombinant) (C-His-Avi) {Biotin} (STJP001661) HEK293
STJP001859 Human NKp30 protein (Recombinant) (Fc-Tag) (STJP001859)
STJP012970 Human CD337/NKp30 protein (Recombinant) (C-His) (STJP012970) Mammalian Cells ELISA/WB
STJP003209 Human CD337/NCR3 protein (Recombinant) (C-His) (STJP003209) Mammalian Cells ELISA/Immunogen/SDS-PAGE/WB

Related Products

!