Human NKG7 protein (Recombinant) (N-GST & C-His) (STJP015896)

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STJP015896
€250.20 - €1,396.20
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Host: E.coli
Applications: ELISA/Immunogen/SDS-PAGE/WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human NKG7-N-GST & C-His protein was developed from e.coli and has a target region of N-GST & C-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: Please contact us for further information.
Gene Symbol: NKG7
Gene ID: 4818
Uniprot ID: NKG7_HUMAN
Immunogen Region: Phe29-Phe61
Immunogen: Homo sapiens (Human)
Function Regulates cytotoxic granule exocytosis in effector lymphocytes, thus acting as a critical mediator of inflammation in a broad range of infectious and non-infectious diseases. Essential for cytotoxic degranulation of natural killer (NK) cells and CD8(+) T-cells and for the activation of CD4(+) T-cells following infection. Plays a critical role in CD8(+) T-cell and NK cell-mediated cytolysis of target cells and contributes to the cytolytic activity via the perforin/granzyme pathway by enhancing exocytosis of LAMP1-carrying lytic granules. Contributes to NK cell-mediated control of cancer metastasis.
Protein Name Protein Nkg7
G-Csf-Induced Gene 1 Protein
Gig-1 Protein
Granule Membrane Protein Of 17 Kda
Gmp-17
Natural Killer Cell Protein 7
P15-Tia-1
Database Links
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Cytolytic Granule Membrane
Alternative Protein Names Protein Nkg7 protein
G-Csf-Induced Gene 1 Protein protein
Gig-1 Protein protein
Granule Membrane Protein Of 17 Kda protein
Gmp-17 protein
Natural Killer Cell Protein 7 protein
P15-Tia-1 protein
NKG7 protein
GIG1 protein

Information sourced from Uniprot.org