| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | < 0.01 EU/Mu g of the protein by LAL method. |
| Immunoreactivity: | Measured by its binding ability in a functional ELISA. Immobilized Human ULBP3 Protein at 2 Mu g/mL (100 Mu L/well) can bind NKG2D-raFc with a linear range of 9.8-2009.2 ng/mL. |
| Gene Symbol: | ULBP3 |
| Gene ID: | 79465 |
| Uniprot ID: | ULBP3_HUMAN |
| Immunogen: | Recombinant Human NKG2D ligand 3/ULBP3 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Gly27-Pro216) of human ULBP-3 (Accession #NP_078794) fused with an Fc, 6×His tag at the C-terminus. |
| Immunogen Sequence: | GRADAHSLWYNFTIIHLPRH GQQWCEVQSQVDQKNFLSYD CGSDKVLSMGHLEEQLYATD AWGKQLEMLREVGQRLRLEL ADTELEDFTPSGPLTLQVRM SCECEADGYIRGSWQFSFDG RKFLLFDSNNRKWTVVHAGA RRMKEKWEKDSGLTTFFKMV SMRDCKSWLRDFLMHRKKRL EPTAPPTMAP |
| Function | Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity. |
| Protein Name | Ul16-Binding Protein 3Alcan-GammaNkg2d Ligand 3N2dl-3Nkg2dl3Retinoic Acid Early Transcript 1n |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-Anchor |
| Alternative Protein Names | Ul16-Binding Protein 3 proteinAlcan-Gamma proteinNkg2d Ligand 3 proteinN2dl-3 proteinNkg2dl3 proteinRetinoic Acid Early Transcript 1n proteinULBP3 proteinN2DL3 proteinRAET1N protein |
Information sourced from Uniprot.org