| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | <0.1 EU/Mu g |
| Immunoreactivity: | Measured by its binding ability in a functional ELISA. Immobilized Human ULBP1 at 2 Mu g/mL (100 Mu L/well) can bind NKG2D with a linear range of 1.95-9.36ng/mL. |
| Gene Symbol: | ULBP1 |
| Gene ID: | 80329 |
| Uniprot ID: | ULBP1_HUMAN |
| Immunogen: | Recombinant Human NKG2D ligand 1/ULBP1 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gly26-Pro215) of human ULBP1 (Accession #NP_079494.1) fused with a 6×His, Avi tag at the C-terminus. |
| Immunogen Sequence: | GWVDTHCLCYDFIITPKSRP EPQWCEVQGLVDERPFLHYD CVNHKAKAFASLGKKVNVTK TWEEQTETLRDVVDFLKGQL LDIQVENLIPIEPLTLQARM SCEHEAHGHGRGSWQFLFNG QKFLLFDSNNRKWTALHPGA KKMTEKWEKNRDVTMFFQKI SLGDCKMWLEEFLMYWEQML DPTKPPSLAP |
| Function | Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity. |
| Protein Name | Ul16-Binding Protein 1Alcan-BetaNkg2d Ligand 1N2dl-1Nkg2dl1Retinoic Acid Early Transcript 1i |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-AnchorEndoplasmic ReticulumIn Cmv-Infected FibroblastsDetected In The Endoplasmic Reticulum/Cis-Golgi |
| Alternative Protein Names | Ul16-Binding Protein 1 proteinAlcan-Beta proteinNkg2d Ligand 1 proteinN2dl-1 proteinNkg2dl1 proteinRetinoic Acid Early Transcript 1i proteinULBP1 proteinN2DL1 proteinRAET1I protein |
Information sourced from Uniprot.org