Human NKCC2 (Na-K-Cl Cotransporter 2) Sandwich ELISA Kit Kit (STJE0010980)

Human NKCC2 (Na-K-Cl Cotransporter 2) Sandwich ELISA Kit Kit (STJE0010980)

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STJE0010980
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Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 13.8pg/mL
Detection Limit: 31.2-2000pg/mL
Short Description : This NKCC2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids..
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: SLC12A1
Gene ID: 6557
Uniprot ID: S12A1_HUMAN
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity Kidney.localizes to the thick ascending limbs (at protein level).
Post Translational Modifications Phosphorylated at Ser-91, Thr-100 and Thr-105 by OXSR1/OSR1 and STK39/SPAK downstream of WNK kinases (WNK1, WNK2, WNK3 or WNK4), promoting its activity.
Function Renal sodium, potassium and chloride ion cotransporter that mediates the transepithelial NaCl reabsorption in the thick ascending limb and plays an essential role in the urinary concentration and volume regulation. Electrically silent transporter system.
Protein Name Solute Carrier Family 12 Member 1
Bumetanide-Sensitive Sodium-(Potassium-Chloride Cotransporter 1
Bsc1
Kidney-Specific Na-K-Cl Symporter
Na-K-2cl Cotransporter 2
Nkcc2
Database Links Reactome: R-HSA-426117
Reactome: R-HSA-5619104
Cellular Localisation Apical Cell Membrane
Multi-Pass Membrane Protein
Alternative ELISA Names Solute Carrier Family 12 Member 1 ELISA kit
Bumetanide-Sensitive Sodium-(Potassium-Chloride Cotransporter 1 ELISA kit
Bsc1 ELISA kit
Kidney-Specific Na-K-Cl Symporter ELISA kit
Na-K-2cl Cotransporter 2 ELISA kit
Nkcc2 ELISA kit
SLC12A1 ELISA kit
NKCC2 ELISA kit
output

Information sourced from Uniprot.org

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