Host: |
HEK293 cells |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Recombinant-Human NKAT-2/KIR2DL3/CD158b2-C-hFc&His protein was developed from hek293 cells and has a target region of C-hFc&His. For use in research applications. |
Formulation: |
Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation. |
Immunoreactivity: |
Measured by its binding ability in a functional ELISA. Immobilized Human KIR2DL3 at 1 Mu g/mL (100 Mu L/well) can bind KIR2DL3 Rabbit pAb with a linear range of 2-54 ng/mL. |
Gene Symbol: |
KIR2DL3 |
Gene ID: |
3804 |
Uniprot ID: |
KI2L3_HUMAN |
Immunogen: |
Recombinant Human NKAT-2/KIR2DL3/CD158b2 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (His22-His245) of human KIR2DL3/CD158b2 (Accession #NP_056952.2) fused with an Fc, 6×His tag at the C-terminus. |
Function | Receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activity of NK cells thus preventing cell lysis. |
Protein Name | Killer Cell Immunoglobulin-Like Receptor 2dl3Cd158 Antigen-Like Family Member B2Kir-023gbKiller Inhibitory Receptor Cl 2-3Nkat2aNkat2bNatural Killer-Associated Transcript 2Nkat-2P58 Natural Killer Cell Receptor Clone Cl-6P58 Nk Receptor Cl-6P58.2 Mhc Class-I-Specific Nk ReceptorCd Antigen Cd158b2 |
Database Links | Reactome: R-HSA-198933 |
Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
Alternative Protein Names | Killer Cell Immunoglobulin-Like Receptor 2dl3 proteinCd158 Antigen-Like Family Member B2 proteinKir-023gb proteinKiller Inhibitory Receptor Cl 2-3 proteinNkat2a proteinNkat2b proteinNatural Killer-Associated Transcript 2 proteinNkat-2 proteinP58 Natural Killer Cell Receptor Clone Cl-6 proteinP58 Nk Receptor Cl-6 proteinP58.2 Mhc Class-I-Specific Nk Receptor proteinCd Antigen Cd158b2 proteinKIR2DL3 proteinCD158B2 proteinKIRCL23 proteinNKAT2 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance