Human Neurogenin-3 protein (Recombinant) (His-Tag) (STJP018598)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human Neurogenin-3-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Denatured |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.25 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol, 0.4M urea |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NEUROG3 |
| Gene ID | 50674 |
| Uniprot ID | NGN3_HUMAN |
| Accession Number | AAH74938.1 |
| Immunogen | Human |
| Immunogen Region | 1-214aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MTPQPSGAPT VQVTRETERS FPRASEDEVT CPTSAPPSPT RTRGNCAEAE EGGCRGAPRK LRARRGGRSR PKSELALSKQ RRSRRKKAND RERNRMHNLN SALDALRGVL PTFPDDAKLT KIETLRFAHN YIWALTQTLR IADHSLYALE PPAPHCGELG SPGGSPGDWG SLYSPVSQAG SLSPAASLEE RPGLLGATSS ACLSPGSL |
Additional Info
| Function | Acts as a transcriptional regulator. Together with NKX2-2, initiates transcriptional activation of NEUROD1. Involved in neurogenesis. Also required for the specification of a common precursor of the 4 pancreatic endocrine cell types. |
| Protein Name | Neurogenin-3Ngn-3Class A Basic Helix-Loop-Helix Protein 7Bhlha7Protein Atonal Homolog 5 |
| Database Links | Reactome: R-HSA-210744Reactome: R-HSA-210746 |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | Neurogenin-3 proteinNgn-3 proteinClass A Basic Helix-Loop-Helix Protein 7 proteinBhlha7 proteinProtein Atonal Homolog 5 proteinNEUROG3 proteinATOH5 proteinBHLHA7 proteinNGN3 protein |
Information sourced from Uniprot.org