| Host: | E.coli |
| Applications: | SDS-PAGE/Denatured |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human Neurogenin-3-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol, 0.4M urea |
| Concentration: | 0.25 mg/mL |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NEUROG3 |
| Gene ID: | 50674 |
| Uniprot ID: | NGN3_HUMAN |
| Immunogen Region: | 1-214aa |
| Accession Number: | AAH74938.1 |
| Immunogen: | Human |
| Immunogen Sequence: | MGSSHHHHHH SSGLVPRGSH MTPQPSGAPT VQVTRETERS FPRASEDEVT CPTSAPPSPT RTRGNCAEAE EGGCRGAPRK LRARRGGRSR PKSELALSKQ RRSRRKKAND RERNRMHNLN SALDALRGVL PTFPDDAKLT KIETLRFAHN YIWALTQTLR IADHSLYALE PPAPHCGELG SPGGSPGDWG SLYSPVSQAG SLSPAASLEE RPGLLGATSS ACLSPGSL |
| Function | Acts as a transcriptional regulator. Together with NKX2-2, initiates transcriptional activation of NEUROD1. Involved in neurogenesis. Also required for the specification of a common precursor of the 4 pancreatic endocrine cell types. |
| Protein Name | Neurogenin-3Ngn-3Class A Basic Helix-Loop-Helix Protein 7Bhlha7Protein Atonal Homolog 5 |
| Database Links | Reactome: R-HSA-210744Reactome: R-HSA-210746 |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | Neurogenin-3 proteinNgn-3 proteinClass A Basic Helix-Loop-Helix Protein 7 proteinBhlha7 proteinProtein Atonal Homolog 5 proteinNEUROG3 proteinATOH5 proteinBHLHA7 proteinNGN3 protein |
Information sourced from Uniprot.org