Human NEK1 protein (Recombinant) (N-GST & C-His) (STJP008507)

SKU:
STJP008507
£328.50 - £1,437.50
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human NEK1-N-GST & C-His protein was developed from e. coli and has a target region of N-GST & C-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: NEK1
Gene ID: 4750
Uniprot ID: NEK1_HUMAN
Immunogen Region: Cys1177-Glu1258
Immunogen: Homo sapiens (Human)
Function Phosphorylates serines and threonines, but also appears to possess tyrosine kinase activity. Involved in DNA damage checkpoint control and for proper DNA damage repair. In response to injury that includes DNA damage, NEK1 phosphorylates VDAC1 to limit mitochondrial cell death. May be implicated in the control of meiosis. Involved in cilium assembly.
Protein Name Serine/Threonine-Protein Kinase Nek1
Never In Mitosis A-Related Kinase 1
Nima-Related Protein Kinase 1
Renal Carcinoma Antigen Ny-Ren-55
Database Links Reactome: R-HSA-9861718
Cellular Localisation Nucleus
Cytoplasm
Cytoskeleton
Microtubule Organizing Center
Centrosome
Associated With The Pericentriolar Material
Localizes To Centrosome During Interphase And Mitosis
Translocated From Cytoplasm To Discrete Nuclear Foci At Sites Of Dna Damage
Alternative Protein Names Serine/Threonine-Protein Kinase Nek1 protein
Never In Mitosis A-Related Kinase 1 protein
Nima-Related Protein Kinase 1 protein
Renal Carcinoma Antigen Ny-Ren-55 protein
NEK1 protein
KIAA1901 protein

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJP011289 Human SOX9, N-GST & C-His protein (Recombinant) (N-GST & C-His) (STJP011289) E. coli
STJP009619 Human WAS protein (Recombinant) (N-GST & C-His) (STJP009619) E. coli
STJP007569 Human MTF1 protein (Recombinant) (N-GST & C-His) (STJP007569) E. coli
STJP007670 Human HAX1 protein (Recombinant) (N-GST & C-His) (STJP007670) E. coli
STJP009046 Human APH1A protein (Recombinant) (N-GST & C-His) (STJP009046) E. coli

Related Products

!