Human NDNF protein (Recombinant) (N-GST) (STJP005739)

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STJP005739
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human NDNF-N-GST protein was developed from e. coli and has a target region of N-GST. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: NDNF
Gene ID: 79625
Uniprot ID: NDNF_HUMAN
Immunogen Region: Met238-Phe331
Immunogen: Homo sapiens (Human)
Post Translational Modifications O-glycosylated.contains heparan sulfate and chondroitin sulfate. N-glycosylated.
Function Secretory protein that plays a role in various cellular processes. Acts as a chemorepellent acting on gonadotropin-releasing hormone (GnRH) expressing neurons regulating their migration to the hypothalamus. Also promotes neuron migration, growth and survival as well as neurite outgrowth and is involved in the development of the olfactory system. May also act through the regulation of growth factors activity and downstream signaling. Also regulates extracellular matrix assembly and cell adhesiveness. Promotes endothelial cell survival, vessel formation and plays an important role in the process of revascularization through NOS3-dependent mechanisms.
Protein Name Protein Ndnf
Neuron-Derived Neurotrophic Factor
Cellular Localisation Secreted
Alternative Protein Names Protein Ndnf protein
Neuron-Derived Neurotrophic Factor protein
NDNF protein
C4orf31 protein
UNQ2748 protein
PRO6487 protein

Information sourced from Uniprot.org

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