| Short Description : | Recombinant-Human NAT12/NAA30-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications: | SDS-PAGE |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Concentration: | 0.25 mg/mL |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% Glycerol, 1mM DTT |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NAA30 |
| Gene ID: | 122830 |
| Uniprot ID: | NAA30_HUMAN |
| Accession Number: | NP_001011713 |
| Immunogen: | Human |
| Immunogen Region: | 1-362aa |
| Immunogen Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMAEVPPG PSSLLPPPAP PAPAAVEPRC PFPAGAALAC CSEDEEDDEE HEGGGSRSPA GGESATVAAK GHPCLRCPQP PQEQQQLNGL ISPELRHLRA AASLKSKVLS VAEVAATTAT PDGGPRATAT KGAGVHSGER PPHSLSSNAR TAVPSPVEAA AASDPAAARN GLAEGTEQEE EEEDEQVRLL SSSLTADCSL RSPSGREV |
| Function | Catalytic subunit of the N-terminal acetyltransferase C (NatC) complex. Catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Leu-Ala and Met-Leu-Gly. N-terminal acetylation protects proteins from ubiquitination and degradation by the N-end rule pathway. Necessary for the lysosomal localization and function of ARL8B sugeesting that ARL8B is a NatC substrate. |
| Protein Name | N-Alpha-Acetyltransferase 30N-Acetyltransferase 12N-Acetyltransferase Mak3 HomologNatc Catalytic Subunit |
| Database Links | Reactome: R-HSA-6811440 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Protein Names | N-Alpha-Acetyltransferase 30 proteinN-Acetyltransferase 12 proteinN-Acetyltransferase Mak3 Homolog proteinNatc Catalytic Subunit proteinNAA30 proteinC14orf35 proteinMAK3 proteinNAT12 protein |
Information sourced from Uniprot.org
