| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity: | Measured by its binding ability in a functional ELISA. Immobilized Human MOG at 1 Mu g/mL (100 Mu L/well) can bind Myelin oligodendrocyte glycoprotein Rabbit mAb with a linear range of 0.98-2.5 ng/mL |
| Determination Method: | <0.1 EU/Mu g |
| Gene Symbol: | MOG |
| Gene ID: | 4340 |
| Uniprot ID: | MOG_HUMAN |
| Immunogen: | Recombinant Human Myelin-oligodendrocyte glycoprotein/MOG Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gly30-Gly154) of human MOG (Accession #NP_996532.2) fused with a 6×His tag at the C-termin |
| Immunogen Region: | Gly30-Gly154 |
| Immunogen Sequence: | GQFRVIGPRHPIRALVGDEV ELPCRISPGKNATGMEVGWY RPPFSRVVHLYRNGKDQDGD QAPEYRGRTELLKDAIGEGK VTLRIRNVRFSDEGGFTCFF RDHSYQEEAAMELKVEDPFY WVSPG |
| Function | Mediates homophilic cell-cell adhesion. Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication. (Microbial infection) Acts as a receptor for rubella virus. |
| Protein Name | Myelin-Oligodendrocyte Glycoprotein |
| Database Links | |
| Cellular Localisation | Isoform 1: Cell MembraneMulti-Pass Membrane ProteinIsoform 5: Cell MembraneIsoform 2: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 3: Cell MembraneIsoform 4: Cell MembraneIsoform 6: Cell MembraneIsoform 7: Cell MembraneIsoform 8: Cell MembraneIsoform 9: Cell Membrane |
| Alternative Protein Names | Myelin-Oligodendrocyte GlycoproteinMOG protein |
Information sourced from Uniprot.org
