| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human MYCN-N-His-SUMO & C-Strep protein was developed from e. coli and has a target region of N-His-SUMO & C-Strep. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | MYCN |
| Gene ID: | 4613 |
| Uniprot ID: | MYCN_HUMAN |
| Immunogen Region: | Asp48-Arg138 |
| Immunogen: | Homo sapiens (Human) |
| Post Translational Modifications | Phosphorylated by GSK3-beta which may promote its degradation. Phosphorylated by AURKA. |
| Function | Positively regulates the transcription of MYCNOS in neuroblastoma cells. |
| Protein Name | N-Myc Proto-Oncogene ProteinClass E Basic Helix-Loop-Helix Protein 37Bhlhe37 |
| Database Links | Reactome: R-HSA-201556Reactome: R-HSA-9839394 |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | N-Myc Proto-Oncogene Protein proteinClass E Basic Helix-Loop-Helix Protein 37 proteinBhlhe37 proteinMYCN proteinBHLHE37 proteinNMYC protein |
Information sourced from Uniprot.org