| Short Description : | Recombinant-Human MVD-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications: | SDS-PAGE |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Concentration: | 0.5 mg/mL |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 20% Glycerol, 1mM DTT |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MVD |
| Gene ID: | 4597 |
| Uniprot ID: | MVD1_HUMAN |
| Accession Number: | NP_002452 |
| Immunogen: | Human |
| Immunogen Region: | 1-400aa |
| Immunogen Sequence: | MGSSHHHHHH SSGLVPRGSH MASEKPLAAV TCTAPVNIAV IKYWGKRDEE LVLPINSSLS VTLHQDQLKT TTTAVISKDF TEDRIWLNGR EEDVGQPRLQ ACLREIRCLA RKRRNSRDGD PLPSSLSCKV HVASVNNFPT AAGLASSAAG YACLAYTLAR VYGVESDLSE VARRGSGSAC RSLYGGFVEW QMGEQADGKD SIARQVAPES HWPELRVLIL VVSAEKKL |
| Tissue Specificity | Expressed in heart, skeletal muscle, lung, liver, brain, pancreas, kidney and placenta. |
| Function | Catalyzes the ATP dependent decarboxylation of (R)-5-diphosphomevalonate to form isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoids and sterol synthesis. |
| Protein Name | Diphosphomevalonate DecarboxylaseMevalonateDiphosphodecarboxylaseMddaseMevalonate Pyrophosphate Decarboxylase |
| Database Links | Reactome: R-HSA-191273Reactome: R-HSA-2426168Reactome: R-HSA-446199 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | Diphosphomevalonate Decarboxylase proteinMevalonate proteinDiphosphodecarboxylase proteinMddase proteinMevalonate Pyrophosphate Decarboxylase proteinMVD proteinMPD protein |
Information sourced from Uniprot.org
