Human MTMR2 protein (Recombinant) (N-His) (STJP008497)

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STJP008497
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Covered by St John's Laboratory Guarantee

Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human MTMR2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: MTMR2
Gene ID: 8898
Uniprot ID: MTMR2_HUMAN
Immunogen Region: Lys85-Glu591
Immunogen: Homo sapiens (Human)
Function Lipid phosphatase that specifically dephosphorylates the D-3 position of phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate, generating phosphatidylinositol and phosphatidylinositol 5-phosphate. Regulates the level of these phosphoinositides critical for various biological processes including autophagy initiation and autophagosome maturation.
Protein Name Phosphatidylinositol-3 -5-Bisphosphate 3-Phosphatase Mtmr2
Myotubularin-Related Protein 2
Phosphatidylinositol-3-Phosphate Phosphatase
Database Links Reactome: R-HSA-1483248
Reactome: R-HSA-1660499
Reactome: R-HSA-1660516
Reactome: R-HSA-1660517
Cellular Localisation Cytoplasm
Early Endosome Membrane
Peripheral Membrane Protein
Perinuclear Region
Cell Projection
Axon
Endosome Membrane
Partly Associated With Membranes
Localizes To Vacuoles In Hypo-Osmotic Conditions
Alternative Protein Names Phosphatidylinositol-3 -5-Bisphosphate 3-Phosphatase Mtmr2 protein
Myotubularin-Related Protein 2 protein
Phosphatidylinositol-3-Phosphate Phosphatase protein
MTMR2 protein
KIAA1073 protein

Information sourced from Uniprot.org

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