Human MTMR2 protein (Recombinant) (N-His) (STJP008497)

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STJP008497
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Short Description :Recombinant-Human MTMR2-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications:ELISA/Immunogen/SDS-PAGE/WB
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Dilution Range:Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol:MTMR2
Gene ID:8898
Uniprot ID:MTMR2_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Lys85-Glu591
Function Lipid phosphatase that specifically dephosphorylates the D-3 position of phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate, generating phosphatidylinositol and phosphatidylinositol 5-phosphate. Regulates the level of these phosphoinositides critical for various biological processes including autophagy initiation and autophagosome maturation.
Protein Name Phosphatidylinositol-3 -5-Bisphosphate 3-Phosphatase Mtmr2
Myotubularin-Related Protein 2
Phosphatidylinositol-3-Phosphate Phosphatase
Database Links Reactome: R-HSA-1483248
Reactome: R-HSA-1660499
Reactome: R-HSA-1660516
Reactome: R-HSA-1660517
Cellular Localisation Cytoplasm
Early Endosome Membrane
Peripheral Membrane Protein
Perinuclear Region
Cell Projection
Axon
Endosome Membrane
Partly Associated With Membranes
Localizes To Vacuoles In Hypo-Osmotic Conditions
Alternative Protein Names Phosphatidylinositol-3 -5-Bisphosphate 3-Phosphatase Mtmr2 protein
Myotubularin-Related Protein 2 protein
Phosphatidylinositol-3-Phosphate Phosphatase protein
MTMR2 protein
KIAA1073 protein

Information sourced from Uniprot.org